Longevity explained

by Sergey Young
4D MOLECULAR THERAPEUTICS

Precision gene therapy company with a transformative and proprietary discovery platform that enables it to harness the power of directed evolution to customize novel adeno-associated virus (AAV) vectors targeted to specific tissue types in order to unlock the full potential of gene therapy for a broad range of rare and large market diseases Co-founded by David Kirn, David Schaffer, Theresa Janke, and Melissa Kotterman in 2013

DEEP LONGEVITY

Longevity-focused AI company that develops a new AI system that can predict an individual’s biological age significantly more accurately than conventional methods, paving the road to discover what biological culprits drive aging-related diseases A spin-off from Insilico Medicine, founded by Alex Zhavoronkov

EKO HEALTH

A health tech company that creates the best-in-class digital stethoscope platform that captures both heart sounds and ECG readings, and is connected to an AI technology that received an FDA clearance for heart disease assessment and monitoring Co-founded by Connor Landgraf, Jason Bellet, Tyler Crouch in 2013

EXO IMAGING

Medical imaging company that develops ultrasound systems and AI for imaging and therapeutic applications, providing physicians a single, handheld, portable device that can be used for the entire body Co-founded by Sandeep Akkaraju, Janusz Bryzek, Yusuf Haque and John Kokulis in 2015

FREENOME

Health technology company that develops next-generation blood tests for early cancer detection powered by a multiomics platform Co-founded by Gabriel Otte, Riley Ennis, and Charles Roberts in 2014

INSILICO MEDICINE

Next-generation artificial intelligence company that utilizes advances in genomics, big data analysis and deep learning for in silico drug discovery and biomarker development for age-related diseases Founded by Alex Zhavoronkov in 2014

JUVENESCENCE

Biopharmaceutical company that builds an ecosystem and diversified pipeline of therapeutics and technologies targeting aging, age-related disease and regeneration Co-founded by Jim Mellon, Gregory Bailey, and Declan Doogan in 2017

LIFE BIOSCIENCES

Biopharmaceutical company that develops therapies for age-related diseases, focusing on the biology of aging and the goal of significantly extending healthy human lifespans through pioneering research and product development Co-founded by Tristan Edwards and David Sinclair in 2017

LYGENESIS

Biotechnology company with an organ regeneration technology platform enabling a patient's lymph nodes to be used as bioreactors to regrow functioning ectopic organs. Currently focused on liver regeneration Co-founded by Michael Hufford and Eric Lagasse in 2017

SIGLION THERAPEUTICS

Biotechnology company developing encapsulated cell therapy platform that combines advanced cell engineering with innovations in bio-compatible materials to provide durable, controllable, and safe treatment for serious chronic diseases without fibrosis or immune rejection. Founded by Flagship Pioneering in conjunction with Robert Langer and Daniel Anderson from MIT in 2016